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Front cover: Double immunostaining of the endothelial marker PECAM-1 (green) and the motor neuron marker Islet-1/2 (red) in the neural tube of the embryonic day 10.5 mouse embryo. Sprouting vessels into the neural tube run along the surface of the Islet-1/2 positive motor neurons, suggesting close interrelationship between angiogenesis and neurogenesis at this site. For details see the article by Nagase et al. in this issue (pp. 595-604).