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Front cover: SPIN90, a 90-kDa Nck-interacting protein with a SH3 domain, participates in receptor-mediated endocytic pathway in fibroblasts. To label endocytic vesicles, GFP-SPIN90 expressing COS-7 cells with PI(4)P5K were incubated with Texas Red-EGF for 10 min, after which cells were fixed and processed. Arrow heads indicate that SPIN90 (green) localizes in the endocytic vesicles containing internalized Texas Red-EGF (red). For detail see the article by S. H. Kim et al. in this issue (pp.1197–1212 ).